Status:
UNKNOWN
Homonymous Hemianopia in Childhood
Lead Sponsor:
Institute of Child Health
Conditions:
Homonymous Hemianopia
Eligibility:
All Genders
5-17 years
Phase:
NA
Brief Summary
The study will consist of two connected components at a single centre. Phase 1 is observational, phenotyping children with Homonymous hemianopia (HH). Phase 2 is a pilot double blind cross over RCT in...
Detailed Description
The project will consist of two connected pieces of work. The primary phase of the study will examine children with a diagnosis of homonymous hemianopia to investigate the clinical spectrum, and under...
Eligibility Criteria
Inclusion
- Phase 1 inclusion criteria:
- Clinical diagnosis of homonymous hemianopia
- Age 5 to 17
- Corrected visual acuity within normal limits for age,
- No evidence of eye pathology (pathology of the eye its self that causes additional visual impairment on top of the homonymous hemianopia) including no nystagmus
- No marked refractive error \> +/-5.00DS
- Complete homonymous hemianopia of more than 6 months - to avoid any natural recovery or adaptation (i.e. in stroke)
- Phase 2 inclusion criteria:
- Participation in phase 1 or copy of a detailed clinical assessment in the last 6 months from GOSH or a PIC site.
- No hemispatial visual neglect detected in phase one or a clinical assessment
- Aged 7 to 17
- Corrected visual acuity within normal limits for age,
- No evidence of eye pathology (pathology of the eye its self that causes additional visual impairment on top of the homonymous hemianopia) including no nystagmus
- No marked refractive error \> +/-5.00DS
- Complete homonymous hemianopia of more than 6 months - to avoid any natural recovery or adaptation (i.e. in stroke)
Exclusion
- Phase 1 exclusion criteria:
- Cannot establish definite clinical diagnosis of homonymous hemianopia
- Have participated in other studies undertaking intervention for homonymous hemianopia
- Reduced corrected visual acuity for age and/or high glasses prescription.
- Eye pathology (that causes additional visual impairment to the homonymous hemianopia) and/or nystagmus
- Homonymous hemianopia incomplete or less than 6 months old
- Suspected or proven deficit of the unaffected hemisphere of the brain
- Phase 2 exclusion criteria:
- No participation in phase 1 or copy of a detailed ophthalmology assessment in the last 6 months from GOSH or a PIC site.
- Hemispatial visual neglect
- Cannot establish definite clinical diagnosis of homonymous hemianopia
- Age/ability/additional disability means cannot give subjective responses
- Have participated in other studies doing intervention for homonymous hemianopia
- Reduced corrected visual acuity for age and/or high glasses prescription
- Eye pathology (that causes additional visual impairment to the homonymous hemianopia) and/or nystagmus
- Homonymous hemianopia incomplete or less than 6 months old
- Suspected or proven deficit of the unaffected hemisphere of the brain
Key Trial Info
Start Date :
May 4 2023
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
July 1 2025
Estimated Enrollment :
25 Patients enrolled
Trial Details
Trial ID
NCT06115317
Start Date
May 4 2023
End Date
July 1 2025
Last Update
November 3 2023
Active Locations (1)
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1
Great Ormond Street Hospital for Chidlren
London, United Kingdom