Status:
COMPLETED
Endometrial Tissues and Mononuclear Cells Receptivity in Pathogenesis of Endometrial Proliferative Processes
Lead Sponsor:
Pirogov Russian National Research Medical University
Conditions:
Endometrial Hyperplasia Without Atypia
Endometrial Hyperplasia With Atypia
Eligibility:
FEMALE
53-80 years
Brief Summary
A prospective observational study of endometrial tissue and peripheral blood mononuclear cells receptivity to sex steroid hormones in postmenopausal patients with endometrial proliferative processes
Detailed Description
Endometrial cancer is in third place among cancer diseases in female population of Russia. The peak morbidity occurs during the postmenopausal period. In this regard, early diagnosis of previous endom...
Eligibility Criteria
Inclusion
- endometrial polyps
- endometrial hyperplasia
- atypical endometrial hyperplasia
- endometrial cancer
Exclusion
- hormonal treatment (estrogen-progestogens, gestagens, gonadotropin-releasing hormone agonists, menopausal hormone therapy and tamoxifen) for 6 months before the study
- uterine fibroids, larger than 6-7 pregnancy weeks
- pathology of the uterine appendages according to ultrasound pelvis
- inflammatory diseases of various localization at the time of taking the material
Key Trial Info
Start Date :
October 1 2012
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
August 1 2022
Estimated Enrollment :
92 Patients enrolled
Trial Details
Trial ID
NCT06115577
Start Date
October 1 2012
End Date
August 1 2022
Last Update
November 15 2023
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