Status:

RECRUITING

Prospective Assessment of HPV Associated Anogenital Pathology in Female Patients and Female Partners of Patients With Confirmed HPV Associated Oropharyngeal Carcinoma, PAP-OP Study

Lead Sponsor:

Mayo Clinic

Conditions:

Oropharyngeal Human Papillomavirus-Positive Squamous Cell Carcinoma

Eligibility:

FEMALE

18+ years

Brief Summary

This study evaluates how often women with throat (oropharyngeal) cancer or who have a partner with oropharyngeal cancer get anogenital infections with high risk, potentially cancer-causing types of hu...

Detailed Description

PRIMARY OBJECTIVES: I. Prospectively determine the incidence of anogenital infection with high-risk HPV serotypes and HPV-associated anogenital lesions in female patients with newly diagnosed HPV(+)O...

Eligibility Criteria

Inclusion

  • \* Female patients with diagnosed HPV(+)OPSCC seen at the Mayo Clinic, Rochester
  • Age ≥ 18
  • Female partners of Mayo Clinic patients with diagnosed HPV(+)OPSCC
  • Patient has given permission to give his/her blood/saliva sample for research testing
  • Ability to complete questionnaire(s) by themselves or with assistance

Exclusion

  • \* HPV(-) OPSCC
  • Unable to provide informed consent
  • Unwilling to attend screening visit at Mayo Clinic site, if indicated
  • Unwilling/unable to complete surveys electronically

Key Trial Info

Start Date :

November 1 2022

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

November 1 2027

Estimated Enrollment :

154 Patients enrolled

Trial Details

Trial ID

NCT06115772

Start Date

November 1 2022

End Date

November 1 2027

Last Update

September 22 2025

Active Locations (1)

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Mayo Clinic in Rochester

Rochester, Minnesota, United States, 55905