Status:

RECRUITING

Immune Profiling for Cancer Immunotherapy Response

Lead Sponsor:

Dartmouth-Hitchcock Medical Center

Conditions:

Cancer

Tumor, Solid

Eligibility:

All Genders

18+ years

Brief Summary

In patients clinically treated with FDA-approved immunotherapy the investigators will assess the predictive value of pre- and on-treatment 1) immune-methylation profiling across cancer types, and 2) i...

Eligibility Criteria

Inclusion

  • Cancer patients receiving or will receive immunotherapy under FDA- approved indication (e.g. checkpoint inhibitor therapy with pembrolizumab, nivolumab, or ipilimumab, or cellular immunotherapy).
  • Participants are eligible regardless of the type of prior therapy (i.e. prior immunotherapy treated participants can be included).

Exclusion

  • Pregnant women/fetuses/neonates
  • Prisoners
  • Decision-impaired individuals

Key Trial Info

Start Date :

October 3 2022

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

January 1 2029

Estimated Enrollment :

1500 Patients enrolled

Trial Details

Trial ID

NCT06116032

Start Date

October 3 2022

End Date

January 1 2029

Last Update

December 16 2025

Active Locations (1)

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Dartmouth-Hitchcock Medical Center

Lebanon, New Hampshire, United States, 03756