Status:

UNKNOWN

Lactate Kinetics as a Predictor of Survival in ACLF With Septic Shock

Lead Sponsor:

Institute of Liver and Biliary Sciences, India

Conditions:

Acute on Chronic Liver Failure

Eligibility:

All Genders

18-70 years

Brief Summary

Shock is a clinical state of tissue hypoxia. This hypoxia may be brought about by either decreased perfusion or the inability of the cell to extract oxygen in the presence of adequate perfusion. This ...

Detailed Description

• We hypothesise that delta lactate at 6 hours would be a better predictor of survival in patients of ACLF with septic shock when compared to admission lactate Aim and Objective - * Aim: To study th...

Eligibility Criteria

Inclusion

  • Patients of Acute on chronic liver failure with septic shock (APASL, Sepsis -3 definitions)
  • Age 18-70yrs
  • Informed Consent

Exclusion

  • Acute coronary syndrome, hemodynamically unstable arrhythmias
  • CKD stage 5
  • COPD with acute exacerbation
  • Acute CVA or Seizures
  • Extremely moribund patients
  • Hepato-cellular carcinoma (HCC), intrahepatic or extrahepatic malignancy
  • Pregnancy
  • Diabetic ketoacidosis

Key Trial Info

Start Date :

November 5 2023

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

August 30 2024

Estimated Enrollment :

100 Patients enrolled

Trial Details

Trial ID

NCT06116305

Start Date

November 5 2023

End Date

August 30 2024

Last Update

November 3 2023

Active Locations (1)

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Page 1 of 1 (1 locations)

1

Institute of Liver & Biliary Sciences (ILBS)

New Delhi, National Capital Territory of Delhi, India, 110070