Status:

RECRUITING

An Observational Study to Learn More About How Well a Treatment Works When Given After Treatment With Atezolizumab and Bevacizumab or Another Similar Combination of Drugs in Adults With Liver Cancer That Cannot be Treated With Surgery

Lead Sponsor:

Bayer

Conditions:

Unresectable Hepatocellular Carcinoma

Eligibility:

All Genders

18+ years

Brief Summary

This is an observational study in which only data will be collected from adults with unresectable hepatocellular carcinoma. These adults should be prescribed a different treatment after treatment with...

Eligibility Criteria

Inclusion

  • Adult patients, ≥ 18 years of age on the day of signing informed consent.
  • Confirmed diagnosis of uHCC, treated in a first-line setting with AB or another approved 1L-IO combo therapy.
  • Decision to initiate treatment with a second-line systemic treatment was made as per investigator's routine treatment practice prior to study enrollment.
  • Signed informed consent or (for patients under legal age) signed informed assent by the patient (where applicable) and signed informed consent by parents / legal guardian.
  • No participation in an investigational program with interventions outside of routine clinical practice.

Exclusion

  • \- Not applicable

Key Trial Info

Start Date :

November 27 2023

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

February 1 2027

Estimated Enrollment :

300 Patients enrolled

Trial Details

Trial ID

NCT06117891

Start Date

November 27 2023

End Date

February 1 2027

Last Update

November 12 2025

Active Locations (20)

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Page 1 of 5 (20 locations)

1

Mercy Medical Center - Medline Healthcare Services LLC

Baltimore, Maryland, United States, 21202

2

University of Michigan Health System

Ann Arbor, Michigan, United States, 48109

3

Roswell Park Comprehensive Cancer Center

Buffalo, New York, United States, 14203

4

University Of Cincinnati Division Of Hematology Oncology - UC Health System

Cincinnati, Ohio, United States, 45219