Status:

COMPLETED

Study Investigating the Safety, Tolerability, PK and Food Effect of BEN8744.

Lead Sponsor:

BenevolentAI Bio

Conditions:

Healthy Volunteer Study

Eligibility:

All Genders

18-65 years

Phase:

PHASE1

Brief Summary

BEN8744 is an experimental new medicine for treating inflammatory bowel diseases such as Ulcerative Colitis. The study will test single and repeated oral doses of BEN8744 or placebo. BEN8744 is a fir...

Detailed Description

This first time in human, study will investigate the safety, tolerability, pharmacokinetics (PK) of BEN8744 after single and multiple ascending oral doses in healthy subjects, in both the fed and fast...

Eligibility Criteria

Inclusion

  • Male or female healthy volunteer in good health
  • Aged 18-65 years
  • Body mass index 18.0-30.9 and weight ≥ 50 kg

Exclusion

  • 1\. Woman who is pregnant or lactating, or pre-menopausal woman who is sexually active and not using a reliable method of contraception

Key Trial Info

Start Date :

August 30 2023

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

March 18 2024

Estimated Enrollment :

76 Patients enrolled

Trial Details

Trial ID

NCT06118385

Start Date

August 30 2023

End Date

March 18 2024

Last Update

May 7 2025

Active Locations (1)

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Page 1 of 1 (1 locations)

1

Hammersmith Medicines Research

London, United Kingdom