Status:

UNKNOWN

Clinical Trial for Evaluating the Effectiveness and Safety of Online caIMR in STEMI Patients

Lead Sponsor:

The Affiliated Hospital of Xuzhou Medical University

Collaborating Sponsors:

RainMed Medical Group

Conditions:

Microvascular Coronary Artery Disease

STEMI

Eligibility:

All Genders

18-80 years

Brief Summary

Despite the success of restoration of epicardial blood flow by the primary percutaneous coronary intervention (PPCI), approximately a half of patients with ST-segment elevation myocardial infarction (...

Detailed Description

Despite the success of restoration of epicardial blood flow by the primary percutaneous coronary intervention (PPCI), approximately a half of patients with ST-segment elevation myocardial infarction (...

Eligibility Criteria

Inclusion

  • Aged between 18 and 80, regardless of gender;
  • Initially diagnosed as STEMI and underwent primary PCI;
  • Voluntarily participated in this trial and signed the informed consent form.

Exclusion

  • Coronary angiography shows that PCI is not suitable;
  • Past history of coronary artery bypass grafting (CABG);
  • Past history of heart failure;
  • Past history of myocardial infarction;
  • Primary or secondary cardiomyopathy or heart valve disease;
  • Patients with renal insufficiency (eGFR\<30ml/min (1.73m\^2)) or patients undergoing dialysis;
  • Cardiogenic shock
  • Persistent left or right coronary ostium lesion after target vessel PCI;
  • Immediate effect of target vessel PCI is unsatisfactory \[such as thrombolysis in myocardial infarction (TIMI) flow \< grade 2, dissection that restricted blood flow, side branch occlusion (diameter\>1.5mm), exist distal embolism or angiographically visible thrombus\];
  • Target vessel exist coronary fistula or myocardial bridge (lumen constriction \>50%);
  • The target vessel cannot clearly expose the lesion in two positions with an included angle ≥ 30 degrees;
  • Severe systemic infection
  • Patients with malignant wasting disease, with an estimated survival of less than 1 year;
  • The subject is participating in another clinical researches, and the primary endpoint has not been reached;
  • The investigator believes that the subject has other conditions that are not suitable for clinical trials.

Key Trial Info

Start Date :

November 1 2023

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

May 31 2025

Estimated Enrollment :

335 Patients enrolled

Trial Details

Trial ID

NCT06118450

Start Date

November 1 2023

End Date

May 31 2025

Last Update

November 8 2023

Active Locations (8)

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Page 1 of 2 (8 locations)

1

Beijing Luhe Hospital.Capital Medical University

Beijing, Beijing Municipality, China

2

Peking University First Hospital

Beijing, Beijing Municipality, China

3

Huai'an First People's Hospital

Huai'an, Jiangsu, China

4

The First People'S Hospital of Lianyungang

Lianyungang, Jiangsu, China