Status:
COMPLETED
Insulin Modelling Based on Plasma Glucose Measures Via a Minimally-Invasive Glucose Sensor
Lead Sponsor:
Singapore Institute of Food and Biotechnology Innovation
Collaborating Sponsors:
Institute for Human Development and Potential (IHDP), Singapore
Conditions:
PreDiabetes
Eligibility:
All Genders
21-60 years
Phase:
NA
Brief Summary
The study aims to evaluate insulin as a potential biomarker for prediabetes in Singapore Chinese subjects.
Detailed Description
The prevalence of type 2 diabetes (T2DM) in Singapore is expected to increase from 400,000 to 1,000,000 individuals by 2050, resulting in nearly US$2 billion in economic costs. Pre-diabetes is defined...
Eligibility Criteria
Inclusion
- Aged 21-60
- Chinese ethnicity
- Male or female
- Adequate fluency in the English language to understand the informed consent process, study instructions and study assessments.
- Sufficient vision and hearing to complete the study procedures
- Willing and able to participate and to give written informed consent
Exclusion
- Diabetes diagnosis based on HbA1c ≥ 6.5%, and fasting plasma glucose ≥ 7.0 mmol/L
- Past (\<3 months prior to the study) or current major metabolic, endocrine, gastrointestinal or cardiovascular disease
- Individuals diagnosed with non-alcoholic fatty liver disease
- Women diagnosed with polycystic ovary syndrome
- Major surgery in the past 2 months
- Past (\<1 month prior to the study) or current use of prescription, over the counter or traditional medication that may influence metabolic or gastrointestinal functioning
- Presence or past history of alcohol or drug addiction
- Smoking
- Pregnant or lactating
- Alcohol intake \>1 units per day
- Body Mass Index \<18.5 kg/m2 or ≥30 kg/m2
- Member of the research team or their immediate family members
Key Trial Info
Start Date :
November 6 2023
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
January 12 2024
Estimated Enrollment :
20 Patients enrolled
Trial Details
Trial ID
NCT06119035
Start Date
November 6 2023
End Date
January 12 2024
Last Update
February 2 2024
Active Locations (1)
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1
Human Development Research Centre, SICS, A*STAR
Singapore, Singapore, 117597