Status:
COMPLETED
Efficacy and Safety of Carica Papaya in Dengue Fever: A Randomised Clinical Trial
Lead Sponsor:
Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh
Collaborating Sponsors:
Institute of Technology Transfer and Innovation (ITTI)
Conditions:
Dengue
Eligibility:
All Genders
18+ years
Phase:
PHASE3
Brief Summary
This will be a placebo-controlled, multicenter-randomized prospective study of CPLE (Carica papaya leaf extract) tabs in dengue patients (WHO-Group A, B). The study will enroll 300 eligible dengue cas...
Detailed Description
Introduction: Dengue is the most important emerging viral disease of humans that, in recent decades, has become a major international public health concern. Dengue is found in tropical and subtropica...
Eligibility Criteria
Inclusion
- Patients who are confirmed dengue fever by NS1 dengue Ag or anti dengue Ab IgM positive
Exclusion
- Children (\<18 years)
- Currently pregnant or lactating
- Patients on steroids, any immunosuppressant
- Patients who received platelet transfusion during the same admission
- Patient with other known causes of thrombocytopenia, including leukemia, ITP
- Patients with alanine aminotransferase (ALT) levels \>150 U/L
- Patient with serum creatine \>1.4 mg/dl
- S. creatine kinase (CK) \>1000 U/L
Key Trial Info
Start Date :
October 1 2023
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
December 27 2023
Estimated Enrollment :
250 Patients enrolled
Trial Details
Trial ID
NCT06121934
Start Date
October 1 2023
End Date
December 27 2023
Last Update
December 29 2023
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
Bangabandhu Sheikh Mujib Medical University
Dhaka, Bangladesh, 1200