Status:
UNKNOWN
Organ Protective Effect of Cetirizine In Patients With Severe Burns
Lead Sponsor:
Ruijin Hospital
Conditions:
Burns
Eligibility:
All Genders
12-90 years
Phase:
PHASE1
PHASE2
Brief Summary
This prospective clinical trial aims to investigate the organ protective effects of cetirizine in patients with severe burns.
Detailed Description
This is a prospective, randomized, single-blind, parallel-controlled clinical trial. The global objective is to compare the organ protective effects of the sedation and analgesia regimen (midazolam, f...
Eligibility Criteria
Inclusion
- Signed and dated informed consent form
- Commitment to comply with the procedures and cooperation during the course
- TBSA \>30% and admitted within the first day after burns
- No severe compound injuries
Exclusion
- History of allergy to drugs in the trial
- Postoperative complications that would interfere with the observation
- Mental illness and severe heart disease, hypertension
- Serious genetic diseases
- Incomplete clinical information (unclear diagnosis, incomplete medical history, incomplete medication records, etc.)
- Pregnancy/lactation
- Malignant tumors
- Organ insufficiency due to previous chronic diseases such as hypertension, diabetes mellitus or non-burning factors
- Serious adverse reactions
- Self-requested withdrawal
Key Trial Info
Start Date :
January 23 2024
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
December 31 2025
Estimated Enrollment :
32 Patients enrolled
Trial Details
Trial ID
NCT06126991
Start Date
January 23 2024
End Date
December 31 2025
Last Update
February 1 2024
Active Locations (1)
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1
Department of Burn, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine
Shanghai, Shanghai Municipality, China