Status:

ACTIVE_NOT_RECRUITING

Study of Near-Infrared Imaging With Indocyanine Green for Detection of Sentinel Lymph Nodes in People With Vulvar Cancer

Lead Sponsor:

Memorial Sloan Kettering Cancer Center

Conditions:

Vulvar Cancer

Eligibility:

FEMALE

18+ years

Phase:

NA

Brief Summary

The purpose of this study is to compare two types of imaging for sentinel lymph node (SLN) mapping in people with early-stage vulvar cancer. The researchers will compare indocyanine green near-infrare...

Eligibility Criteria

Inclusion

  • ≥18 years of age
  • Newly diagnosed with vulvar cancer and scheduled to undergo SLN biopsy (patients with squamous cell carcinomas and melanomas will be included)
  • Primary tumor ≤4 cm in size
  • For patients with squamous cell carcinoma, \>1 mm of invasion is required

Exclusion

  • Clinically or radiographically enlarged inguinofemoral lymph nodes (if imaging is performed)
  • Presence of distant metastases
  • Absolute contraindication to radiocolloid Tc-99 or ICG
  • Nonsquamous or nonmelanoma histologic subtype

Key Trial Info

Start Date :

November 6 2023

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

November 1 2026

Estimated Enrollment :

22 Patients enrolled

Trial Details

Trial ID

NCT06127836

Start Date

November 6 2023

End Date

November 1 2026

Last Update

November 5 2025

Active Locations (8)

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Page 1 of 2 (8 locations)

1

Memorial Sloan Kettering Basking Ridge (Limited Protocol Activities)

Basking Ridge, New Jersey, United States, 07920

2

Memorial Sloan Kettering Monmouth (Limited Protocol Activities)

Middletown, New Jersey, United States, 07748

3

Memorial Sloan Kettering Bergen (Limited Protocol Activities)

Montvale, New Jersey, United States, 07645

4

Memorial Sloan Kettering Suffolk - Commack (Limited Protocol Activities)

Commack, New York, United States, 11725