Status:

RECRUITING

Influence of Hypoxic, Normobaric and Hypobaric Training on the Immunometabolism of Post-covid-19 Athletes

Lead Sponsor:

Faculdade de Motricidade Humana

Collaborating Sponsors:

University of Sao Paulo

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior.

Conditions:

Normobaric Hypoxia

Hypoventilation

Eligibility:

All Genders

18-30 years

Phase:

NA

Brief Summary

COVID-19 has significantly impacted sports globally, with event postponements, training disruptions, and wide-ranging concerns. SARS-CoV-2 infection can result in hyperinflammation and cardiopulmonary...

Detailed Description

Covid-19, caused by SARS-CoV-2, can progress to pulmonary hyperinflammation and cardiopulmonary changes, with hypoxia being one of the main signs of worsening. In hypoxia, there is activation of HIF-1...

Eligibility Criteria

Inclusion

  • more than 5 years of training experience in an resistance modality;
  • participates in national or international championships regularly;
  • athletes convalescing from covid-19, at least 30 days after diagnosis and/or hospital discharge;
  • manifested mild to severe symptoms;
  • vaccinated or not against SARS-CoV-2;
  • antigen self-test for SARS-CoV-2 negative.

Exclusion

  • athletes who have had an acclimatization experience or exposure to altitude lasting more than 10 days in the last 6 months;
  • contain signs or symptoms of acute covid-19;
  • present a positive SARS-CoV-2 antigen self-test;
  • pregnant or postpartum women;
  • use anti-inflammatory or immunosuppressive medications.

Key Trial Info

Start Date :

January 3 2024

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

June 1 2024

Estimated Enrollment :

60 Patients enrolled

Trial Details

Trial ID

NCT06128941

Start Date

January 3 2024

End Date

June 1 2024

Last Update

February 22 2024

Active Locations (1)

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1

Faculty of Human Kinetics

Lisbon, Portugal, 1495-002 Cruz-Quebrada