Status:
RECRUITING
Super-Resolution Ultrasound of the Brain in 3D
Lead Sponsor:
Assistance Publique - Hôpitaux de Paris
Collaborating Sponsors:
Centre National de la Recherche Scientifique, France
Conditions:
Cerebral Stroke
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
The goal of this proof of concept study is to determine if the visualization of the middle cerebral artery and its perforators, through 3D transtemporal ultrasound imaging, is possible thanks to an of...
Eligibility Criteria
Inclusion
- Patient aged 18 and over
- Hospitalized patient with ischemic stroke in the deep territory of the middle cerebral artery
- Patient with lesion observable on MRI
- Patient included between 24 hours and 7 days after the ischemic stroke
- Patient with a temporal window which allows soundproofing of the polygon of Willis and the middle cerebral artery
- Patient having signed free, informed and written consent
- Patient affiliated to a social security system (excluding AME)
Exclusion
- Contralateral middle cerebral artery territory stroke or contralateral middle cerebral artery occlusion
- Patient with contraindication to Doppler ultrasound with contrast (right-left shunt, severe pulmonary arterial hypertension)
- Patient with hypersensitivity to the active princip of Sonovue (sulfur hexafluoride) or these excipients
- Patient with uncontrolled systemic hypertension
- Patient with respiratory distress syndrome
- Patient under guardianship or curatorship
- Pregnant or breastfeeding patient (positive blood pregnancy test during hospitalization)
- Patient with damaged skin at the temporal level
- Patient having presented in the 7 days preceding inclusion an acute coronary syndrome or suffering from unstable ischemic heart disease
Key Trial Info
Start Date :
March 22 2024
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
February 1 2025
Estimated Enrollment :
20 Patients enrolled
Trial Details
Trial ID
NCT06133179
Start Date
March 22 2024
End Date
February 1 2025
Last Update
September 19 2024
Active Locations (1)
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1
Hôpital Bichat
Paris, Île-de-France Region, France, 75018