Status:
RECRUITING
The Bipolar Lithium Imaging Scan Study.
Lead Sponsor:
Leiden University Medical Center
Collaborating Sponsors:
PsyQ
GGZ Rivierduinen
Conditions:
Bipolar Disorder I or II
Eligibility:
All Genders
18+ years
Brief Summary
The main goal of this study is to determine if brain lithium-concentrations predict clinical lithium treatment-response. Secondary, to study correlations between intracerebral distribution-patterns of...
Detailed Description
Introduction Lithium treatment is considered the first-line pharmacological treatment for bipolar disorder. However, individual responses vary greatly, which undermines the ability to achieve rapid st...
Eligibility Criteria
Inclusion
- age 18 years or above,
- a clinical diagnosis of bipolar disorder type I or type II ,
- having reached stable therapeutic serum lithium concentrations (reference values 0.6-1.0 mM in age to 65 years; 0.4-0.8 in age 65 years and above) within four weeks prior to study participation, and
- provided written informed consent.
Exclusion
- insufficient comprehension of the Dutch language,
- unable to provide informed consent,
- drug or alcohol abuse over a period of two weeks prior to study participation, and
- meeting any exclusion criterium for MR imaging.
Key Trial Info
Start Date :
March 13 2024
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
March 1 2028
Estimated Enrollment :
80 Patients enrolled
Trial Details
Trial ID
NCT06134349
Start Date
March 13 2024
End Date
March 1 2028
Last Update
December 13 2024
Active Locations (1)
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1
Leiden University Medical Center
Leiden, South Holland, Netherlands, 2333 ZA