Status:

UNKNOWN

Immune Regulation in Chronic Aspergillus Infection After COVID-19 Infection

Lead Sponsor:

Taipei Veterans General Hospital, Taiwan

Collaborating Sponsors:

National Science and Technology Council

Conditions:

Aspergillosis

Eligibility:

All Genders

20+ years

Brief Summary

This study aims to collect clinical cases and follow-up data from patients with chronic pulmonary aspergillosis, post-COVID-19 aspergillosis, and post-COVID-19 patients without aspergillosis. Using in...

Eligibility Criteria

Inclusion

  • Confirmed cases include patients diagnosed with pulmonary aspergillosis, acute or subacute Aspergillus infections, and aspergillosis in other anatomical sites (such as sinuses, middle ear, liver). Additionally, this study will enroll patients with chronic obstructive pulmonary disease (COPD), asthma, or those undergoing treatment for pulmonary tuberculosis who continue to exhibit worsening pulmonary radiological findings without a clear etiology, necessitating hospitalization or outpatient care for unexplained community-acquired pneumonia. Patients with bronchiectasis, emphysema, pulmonary fibrosis, or other chronic pulmonary conditions who are under continuous follow-up and treatment at our institution will also be included if clinically diagnosed with aspergillosis.
  • The control group will consist of patients who, based on clinical evidence, have no history of prior exposure to Aspergillus or aspergillosis infection after contracting COVID-19.

Exclusion

  • Individuals aged below 20, pregnant women, patients with advanced-stage (stage II and above) lung cancer, individuals diagnosed with malignancies, patients with mental health disorders requiring consent from a legal guardian for participation, and those in critical end-stage conditions.

Key Trial Info

Start Date :

March 23 2023

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

December 31 2025

Estimated Enrollment :

100 Patients enrolled

Trial Details

Trial ID

NCT06135597

Start Date

March 23 2023

End Date

December 31 2025

Last Update

November 18 2023

Active Locations (1)

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1

Shiang Fen Huang

Taipei, Taiwan, 112