Status:
UNKNOWN
Exercise Timing and the Circadian Clock in Individuals With Type 2 Diabetes and Those at Risk
Lead Sponsor:
Faculdade de Motricidade Humana
Collaborating Sponsors:
Fundação para a Ciência e a Tecnologia
Conditions:
Diabetes Mellitus, Type 2
Eligibility:
All Genders
55-75 years
Phase:
NA
Brief Summary
Many investigations have been done to determine the exercise that can elicit the greatest benefits on glycemic control and metabolic health, with findings suggesting that incorporation of higher inten...
Detailed Description
To detect a predicted mean difference in 24-hour area under the curve (AUC) continuous glucose measure (CGM)-based glucose of 1.0 mmol/L with a within patient standard deviation (SD) of 0.85 mmol/L (2...
Eligibility Criteria
Inclusion
- Inclusion Criteria (Group 1):
- previous diagnosis of T2DM
- currently taking metformin (Group 1 only);
- Adults aged 55 to 75 years
- Physically inactive people (i.e. with less than 20 minutes per day of exercise, maximum 3 days per week)
- Exclusion Criteria (Group 1):
- Use of exogenous insulin and taking any other antihyperglycemic medication beyond metformin
- having major micro- or macro-vascular complications from T2DM
- History of cardiovascular incidents
- People with motor limitations (musculoskeletal or neurological) that limit the practice of physical exercise
- inability to provide informed consent
- Inclusion Criteria (Group 2):
- BMI ≥25 without diagnosis of T2DM
- Adults aged 55 to 75 years
- Physically inactive people (i.e. with less than 20 minutes per day of exercise, maximum 3 days per week)
- Exclusion Criteria (Group 2):
- History of cardiovascular incidents
- People with motor limitations (musculoskeletal or neurological) that limit the practice of physical exercise
- inability to provide informed consent
Exclusion
Key Trial Info
Start Date :
January 1 2024
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
December 1 2024
Estimated Enrollment :
34 Patients enrolled
Trial Details
Trial ID
NCT06136013
Start Date
January 1 2024
End Date
December 1 2024
Last Update
November 18 2023
Active Locations (1)
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1
Faculdade de Motricidade Humana
Cruz Quebrada, Oeiras, Portugal, 1409-002