Status:
RECRUITING
AvoCog - the Effect of Daily Avocado Intake on Cognitive Function in Older Adults
Lead Sponsor:
University of Kansas Medical Center
Collaborating Sponsors:
Avocado Nutrition Center
Conditions:
Brain Aging
Eligibility:
All Genders
65-85 years
Phase:
NA
Brief Summary
The goal of this clinical trial is to determine if adding avocados to the diet of impacts cognition in 70 older adults, age 65-85, without dementia. We will test for change in functional MRI, cognitiv...
Eligibility Criteria
Inclusion
- Males and females aged 65-85 years
- Good general health with no concomitant disease
- BMI 18.5 - 35 kg/m2
- Mini Mental State Exam ≥26
- Reports consuming ≤2 medium avocados per month
- Reports consuming ≤3 servings of carotenoid-rich foods per week and ≤3 servings of fruits and vegetables per day
- Skin carotenoid content \<400
Exclusion
- Unwilling or unable to consume avocado
- Latex allergy
- Consistently taking lutein + zeaxanthin supplements
- Skin carotenoid content ≥400
- Central neurological disease such as Alzheimer's disease, Parkinson's disease, multiple sclerosis, stroke, brain tumor, etc.
- Serious medical risk: cancer requiring chemotherapy or radiation within the past 5 years, recent cardiac event (i.e. heart attack, etc.)
- Diabetes mellitus or uncontrolled hypertension
- Use of psychoactive or investigational medications
- Consumption of ≥3 alcoholic drinks per day or substance abuse
- Unable to undergo MRI
Key Trial Info
Start Date :
April 9 2024
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
December 1 2025
Estimated Enrollment :
70 Patients enrolled
Trial Details
Trial ID
NCT06137339
Start Date
April 9 2024
End Date
December 1 2025
Last Update
August 22 2024
Active Locations (1)
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1
University of Kansas Medical Center
Kansas City, Kansas, United States, 66160