Status:
RECRUITING
The Effects of Anesthetics on Brain Network Connectivity in Patients With Supratentorial Glioma
Lead Sponsor:
Beijing Tiantan Hospital
Conditions:
Brain Network Connectivity
Postoperative Delirium
Eligibility:
All Genders
18+ years
Brief Summary
Perioperative anesthesia can affect postoperative cognitive function. In our previous study, intraoperative dexmedetomidine (Dex) infusion reduced the incidence of delirium within the first 5 days aft...
Eligibility Criteria
Inclusion
- Diagnosed as unilateral supratentorial glioma by MRI
- Selective operation
- Age over 18 years old
- ASA I-II
- Right handedness
Exclusion
- History of cerebrovascular disease, brain trauma, chemotherapy and radiotherapy, or psychotropic drugs
- History of intracranial surgery
- Drug and/or alcohol abuse
- History of dementia or mental illness
- Pregnant or lactating women
- Contraindications for MRI
- Severe bradycardia (heart rate less than 40 beats per minute), sick sinus syndrome or second-to-third degree atrioventricular block
- Severe hepatic or renal dysfunction
Key Trial Info
Start Date :
August 31 2023
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
December 31 2025
Estimated Enrollment :
120 Patients enrolled
Trial Details
Trial ID
NCT06138340
Start Date
August 31 2023
End Date
December 31 2025
Last Update
February 14 2025
Active Locations (1)
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1
Beijing Tian Tan Hospital, Capital Medical University
Beijing, Beijing Municipality, China, 100070