Status:
RECRUITING
Comparing the Effect of siSPARC Microneedle Patch Versus siSPARC+siLR4A Microneedle Patch on Post-surgical Scars
Lead Sponsor:
National Skin Centre
Conditions:
Keloid
Wound Heal
Eligibility:
All Genders
21-75 years
Phase:
PHASE2
Brief Summary
This randomized, double-blind controlled study aims to compare the effect on appearance of post- surgical scars between daily application of siSPARC microneedle patch versus siSPARC + siLR4A microneed...
Detailed Description
This is an 8-week, single centre double-blinded intra-individually controlled trial to compare the effect of daily application of siSPARC microneedle patch versus siSPARC + siLR4A microneedle patch on...
Eligibility Criteria
Inclusion
- Adult
- Age 21-75
- 2 weeks (+/- 7 days) after surgical operation with incision into the dermis
- Post-stitch removal when stitches were applied
- Wound closure/union achieved
Exclusion
- Pregnant or lactating participant
- Participants with wound infection
- Participants assessed to be uncooperative or unable to self-administer the interventions
- Participants with known contact allergy to ingredients in the patch formulation (comprising hyaluronic acid, siRNA and glue) and/or isopropyl alcohol
- Participants who are unable to personally consent (for e.g., cognitively impaired)
Key Trial Info
Start Date :
November 14 2023
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
November 14 2024
Estimated Enrollment :
50 Patients enrolled
Trial Details
Trial ID
NCT06138964
Start Date
November 14 2023
End Date
November 14 2024
Last Update
June 24 2024
Active Locations (1)
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1
National Skin Centre
Singapore, Singapore, 308205