Status:
RECRUITING
Exploring the Efficacy, Safety and Cost-effectiveness Analysis of Cadonilimab in the Treatment of Cervical Cancer
Lead Sponsor:
Fujian Cancer Hospital
Collaborating Sponsors:
Fujian Medical University Affiliated Nanping First Hospital
The First Hospital Affiliated to Fujian Medical University
Conditions:
Cervical Cancer
Eligibility:
FEMALE
18-80 years
Brief Summary
Cadonilimab, a PD-1/CTLA-4 bi-specific antibody, is being developed by Akeso, Inc. for the treatment of a range of solid tumors, including cervical cancer, lung cancer, gastric/gastroesophageal juncti...
Detailed Description
1. To explore the efficacy of Cadonilimab in the treatment of persistent, recurrent or metastatic cervical cancer. The size of each diameter of the tumor before and after treatment was measured on...
Eligibility Criteria
Inclusion
- •Persistent, recurrent or metastatic cervical cancer;
- The pathological types are squamous cell carcinoma, adenocarcinoma, and adenosquamous carcinoma;
- No combination with other multiple primary cancers;
- MRI before treatment Or CT examination, according to RECIST evaluation standards, there is at least one measurable lesion;
- ECOG score 0-1 points.
- Subjects gave informed consent, voluntarily cooperated with clinical follow-up, and signed informed consent forms.
Exclusion
- Patients with other histopathological types of cervical cancer, such as small cell carcinoma, clear cell carcinoma, sarcoma, etc.;
- Previous treatment with immune checkpoint inhibitors;
- There are drug contraindications, such as liver function Insufficiency, renal insufficiency, etc.
- The patient withdraws the informed consent;
- The researcher determines that the patient is not suitable to participate in this clinical study.
Key Trial Info
Start Date :
September 7 2024
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
December 1 2026
Estimated Enrollment :
200 Patients enrolled
Trial Details
Trial ID
NCT06140589
Start Date
September 7 2024
End Date
December 1 2026
Last Update
September 19 2024
Active Locations (1)
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1
No. 420 Fuma Road, Jin'an District, Fuzhou City, Fujian Province
Fuzhou, Fujian, China, 350074