Status:

COMPLETED

Feasibility of Bronchial Washing Fluid for Molecular Testing With Next Generation Sequencing in Lung Cancer

Lead Sponsor:

Pusan National University Hospital

Conditions:

Lung Cancer

Eligibility:

All Genders

20+ years

Phase:

NA

Brief Summary

This is a single center, clinical trial evaluating the relevance of intratumoral washing for detection of generic alteration with Next Generation Sequencing.

Detailed Description

This is a prospective, single-arm, open-label study to assess evaluate the relevance of intratumoral washing by ultrathin bronchoscopy (outer diameter; 3mm) for detection of genetic alterations using ...

Eligibility Criteria

Inclusion

  • Age ≥ 20 years
  • Obtained written informed consent
  • No contraindication to bronchoscopy
  • Subjects suspected of having lung cancer on computed tomography or diagnosed with lung cancer by histology or cytology
  • Subjects planning to undergo tissue or liquid biopsy for genetic alteration with Next Generation Sequencing

Exclusion

  • Subjects who withdraw informed consent
  • Subjects who are unable to undergo liquid biopsy (plasma) and tissue biopsy for genetic alteration with Next Generation Sequencing based on the investigator's judgement
  • Subjects diagnosed with a cancer other than non-small cell lung cancer from the lung tissue lesion
  • Subjects diagnosed with a benign lesion from the lung tissue lesion

Key Trial Info

Start Date :

November 30 2023

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

December 31 2024

Estimated Enrollment :

65 Patients enrolled

Trial Details

Trial ID

NCT06141005

Start Date

November 30 2023

End Date

December 31 2024

Last Update

August 15 2025

Active Locations (1)

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Page 1 of 1 (1 locations)

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Pusan National University hospital

Busan, South Korea, 49241

Feasibility of Bronchial Washing Fluid for Molecular Testing With Next Generation Sequencing in Lung Cancer | DecenTrialz