Status:

COMPLETED

Cognitive Function and Glymphatic System in Children with Epilepsy

Lead Sponsor:

Ege University

Conditions:

Epilepsy

Cognitive Dysfunction

Eligibility:

All Genders

8-17 years

Phase:

NA

Brief Summary

Epilepsy, one of the most common neurological disorders in childhood, is a chronic brain disease characterized by neurobiological, psychological and cognitive effects. Neuropeptide-Y (NPY) and neural ...

Eligibility Criteria

Inclusion

  • Diagnosed with absence and rolandic type epilepsy according to the International League Against Epilepsy (ILAE) classification.
  • No previous respiratory physiotherapy.
  • Maximal Inspiratory Pressure (MIP) value is below the expected value according to age and gender.
  • Co-operative.

Exclusion

  • Diagnosed with respiratory system disease.
  • Has kyphoscoliosis and/or advanced postural alignment problems that affect respiratory function.
  • Have severe mental problems.
  • Receiving ketogenic diet application.
  • Have any neuromuscular disease.
  • Have severe cardiac involvement, pulmonary embolism, mesenteric or portal thrombosis.
  • Diagnosis of inflammatory disease or C-reactive protein (CRP) analysis above normal limits.
  • The presence of orthopedic surgery.

Key Trial Info

Start Date :

March 1 2024

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

September 29 2024

Estimated Enrollment :

20 Patients enrolled

Trial Details

Trial ID

NCT06143241

Start Date

March 1 2024

End Date

September 29 2024

Last Update

October 15 2024

Active Locations (1)

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Ege University

Izmir, Bornova, Turkey (Türkiye), 35080