Status:
UNKNOWN
Reconsolidation-Based Intervention for Traumatic Memories
Lead Sponsor:
Shenzhen Kangning Hospital
Collaborating Sponsors:
Science and Technology Innovation Commission of Shenzhen Municipality
Conditions:
Depression
Eligibility:
All Genders
18-25 years
Phase:
NA
Brief Summary
The goal of this clinical trial is to test the effect and underlying mechanism of reconsolidation-based cognitive reappraisal for traumatic memories in patients with major depression disorder. The mai...
Detailed Description
There are three sub-trials in this study. Participants in the first trial will learn the fear of emotional faces based on the Pavlovian conditioned fear learning paradigm. Using an inter-subject exper...
Eligibility Criteria
Inclusion
- Clinical diagnosis of major depression disorder
- Must have normal vision or corrected vision
Exclusion
- Have physical diseases or other mental disorders
- Be pregnant, breastfeeding or do not have menstruation
- Drink alcohol or smoke within 24 hours before the experiment
- Participated in similar experiments before.
- History of severe cardiovascular and cerebrovascular diseases, stroke and other neurological diseases, and history of digestive system diseases.
- Severe hearing and vision impairment.
- Have metal implants in the body, such as non-removable dentures, scaffolds, steel plates, joint metal replacements, etc.
- Have Claustrophobia
- Have acute or chronic disease or infection
Key Trial Info
Start Date :
December 1 2023
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
September 1 2025
Estimated Enrollment :
390 Patients enrolled
Trial Details
Trial ID
NCT06143800
Start Date
December 1 2023
End Date
September 1 2025
Last Update
November 22 2023
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