Status:

COMPLETED

Sequences of Aerobic and Resistance Exercise and Cardio-metabolic Functions in T2D

Lead Sponsor:

Zhejiang University

Collaborating Sponsors:

Nanjing Sport Institute

Karolinska Institutet

Conditions:

Type 2 Diabetes

Eligibility:

All Genders

50-70 years

Phase:

NA

Brief Summary

Aerobic exercise and resistance exercise are two types of exercise commonly used in physical conditioning. Compared to aerobic exercise, a combination of aerobic and resistance exercise has been linke...

Detailed Description

Objectives: This randomized study aims to explore the effects of aerobic and resistance training sequences on glycemic control among type 2 diabetes (T2D) patients through an 8-wk combined aerobic an...

Eligibility Criteria

Inclusion

  • Age 50-70 years;
  • Type 2 diabetes diagnosed as: random blood glucose ≥11.1mmol/L (200mg/dL) or fasting blood glucose ≥7.0mmol/L (126mg/L) or oral glucose tolerance test (2h) ≥11.1mmol/L (200mg/dL) or glycated hemoglobin (HbA1c) ≥ 6.5%;
  • The course of type 2 diabetes lasted for one year or longer;
  • Willing to participate and sign the informed consent form voluntarily

Exclusion

  • Type 1 diabetes;
  • Fasting blood glucose (FBG)\>16.7mmol/L;
  • Severe complications of diabetes such as acute infection, diabetic ketoacidosis, and plantar lesions;
  • Severe kidney disease, cardiovascular and cerebrovascular diseases as identified by a specialist;
  • Musculoskeletal, neurological, psychiatric or other disorders which limit the ability to exercise as identified by a specialist;
  • Doing physical exercise regularly (≥ 3 times per week, at least 1 hour per session of moderate to vigorous activities);
  • Currently under dietary program for weight loss;
  • Systolic blood pressure ≥160 mmHg and/or diastolic blood pressure ≥100 mmHg at rest;
  • Abnormal electrocardiogram (rest and exercise);
  • Other comorbidities or medications irrelevant to diabetes treatment that may influence glycemia during the past 6 months

Key Trial Info

Start Date :

September 25 2023

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

July 2 2024

Estimated Enrollment :

56 Patients enrolled

Trial Details

Trial ID

NCT06145542

Start Date

September 25 2023

End Date

July 2 2024

Last Update

April 3 2025

Active Locations (1)

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Maigaoqiao Community Health Service Center

Nanjing, Jiangsu, China, 210000