Status:
COMPLETED
Effect of Smoking Cessation on Salivary IL-1β and PGE-2 Levels Following Non-Surgical Periodontal Therapy
Lead Sponsor:
October 6 University
Collaborating Sponsors:
Ain Shams University
Misr University for Science and Technology
Conditions:
Periodontal Diseases
Smoking Cessation
Eligibility:
All Genders
20-50 years
Phase:
NA
Brief Summary
The aim of this study is to evaluate the effect of smoking cessation on inflammatory markers following non-surgical treatment of periodontal disease. This is to assess the period of smoking abstinence...
Eligibility Criteria
Inclusion
- Patients with advanced chronic periodontitis upon clinical examination with clinical attachment loss (CAL) more than 5 mm.
- Patients willing to quit smoking to be included in two groups, while patients unwilling to quit smoking to be included in the third group, and the non-smokers as the fourth group.
Exclusion
- Any systemic illness known to affect the outcome.
- Systemic antimicrobial or anti-inflammatory drug therapy within the last 3 months prior to the study.
- Patients unable to perform routine oral hygiene procedures.
- Patients using other forms of tobacco.
Key Trial Info
Start Date :
January 1 2021
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
February 28 2022
Estimated Enrollment :
40 Patients enrolled
Trial Details
Trial ID
NCT06145685
Start Date
January 1 2021
End Date
February 28 2022
Last Update
November 24 2023
Active Locations (1)
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1
Ain Shams University
Cairo, Egypt, 11566