Status:
RECRUITING
Clinical Application of Cytokine Adsorption Technique in AIDS Patients With Severe Pneumonia and/or Septic Shock
Lead Sponsor:
Guangzhou 8th People's Hospital
Conditions:
AIDS Pneumonia
Septic Shock
Eligibility:
All Genders
18-65 years
Brief Summary
Observing the Real-World Application Effectiveness of Cytokine Immune Adsorption Technology in AIDS Patients with Severe Pneumonia or septic shock.
Detailed Description
This is a prospective, single-center, non-randomized, clinical observational cohort study primarily focused on observing the clinical effects of cytokine adsorption technology in patients with AIDS co...
Eligibility Criteria
Inclusion
- Confirmed HIV infection;
- Progression to AIDS stage: CD4+ count \<200 cells/ul and/or occurrence of AIDS opportunistic infections;
- Age between 18 and 65 years;
- Meeting the diagnosis of severe pneumonia or septic shock:
- The criteria for severe pneumonia diagnosis refer to the 2021 ATS (American Thoracic Society) and IDSA (Infectious Diseases Society of America) guidelines for the treatment of community-acquired pneumonia;
- The criteria for septic shock refer to the Chinese Society of Critical Care Medicine's "Chinese Guidelines for the Emergency Treatment of Sepsis/Septic Shock (2018).
Exclusion
- Coexisting central nervous system lesions, severe liver disease, or cirrhosis;
- Concurrent AIDS-related or unrelated tumors;
- Women who are pregnant or breastfeeding;
- Severe underlying diseases of the heart, lungs, liver, kidneys, etc.;
- Alcohol abuse or drug use;
- The researcher believes that the overall condition of the subject affects the evaluation and completion of the trial.
Key Trial Info
Start Date :
October 23 2023
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
October 23 2027
Estimated Enrollment :
60 Patients enrolled
Trial Details
Trial ID
NCT06145828
Start Date
October 23 2023
End Date
October 23 2027
Last Update
November 24 2023
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
Guangzhou Eighth People's Hospital, Guangzhou Medical University
Guangzhou, Guangdong, China, 510060