Status:
RECRUITING
Heme and Non-heme Iron Intakes, Gut Microbiota, and Influence on Host Iron Absorption
Lead Sponsor:
Cornell University
Conditions:
Anemia, Iron Deficiency
Iron Overload
Eligibility:
All Genders
18-40 years
Brief Summary
The FeMicrobiome study will evaluate gut microbiome features and their relationships with dietary iron absorption in healthy adults. The investigators hypothesize that (1) the gut microbiota can be sh...
Detailed Description
Iron is an essential micronutrient ingested as either heme iron (from animal products) or non-heme iron (from both plant and animal sources). Humans have no regulatable means of eliminating absorbed i...
Eligibility Criteria
Inclusion
- Healthy adults
- Age between 18- 40y
- Non-smoking
- Not currently taking vitamin, mineral, prebiotic, and probiotic supplements.
- Females: premenopausal and not pregnant or lactating
- No preexisting medical complications (such as eating disorders, hemoglobinopathies, malabsorption diseases, steroid use, substance abuse history, or taking medications known to influence iron homeostasis)
- Body mass index (BMI) between 18 - 27 kg/m2.
Exclusion
- BMI \<18 or \> 27 kg/m2,
- Age \<18 y or \> 40y,
- Smoking
- Pregnancy, lactating
- Have gastrointestinal disorders/malabsorption diseases/hemoglobinopathies/dietary restrictions/steroid use/ medication use of medications known to impact iron status, iron utilization or inflammatory status
- Currently take vitamin, mineral, prebiotic, and probiotic supplements.
- Recently received antibiotic treatment
Key Trial Info
Start Date :
January 15 2023
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
January 14 2026
Estimated Enrollment :
120 Patients enrolled
Trial Details
Trial ID
NCT06146608
Start Date
January 15 2023
End Date
January 14 2026
Last Update
February 24 2025
Active Locations (1)
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1
Cornell University
Ithaca, New York, United States, 14853