Status:
UNKNOWN
Comparison of the Effect of Two Interventions on Liver Frailty Index in Pre-frail and Frail Cirrhotic Patients Enlisted for Liver Transplantation
Lead Sponsor:
Pontificia Universidad Catolica de Chile
Conditions:
Cirrhosis, Liver
Eligibility:
All Genders
50+ years
Phase:
NA
Brief Summary
The goal of this prospective, double blind randomized clinical trial is to compare the effectiveness of two interventions in improve frailty (measured by Liver Frailty Index) and quality of life (meas...
Detailed Description
Comparison of the effect of two interventions on Liver Frailty Index in pre-frail and frail cirrhotic patients enlisted for liver transplantation. Frailty is a concept derived from geriatrics that tr...
Eligibility Criteria
Inclusion
- Presence of cirrhosis.
- Over 50 years old.
- Liver Frailty Index of 3.2 points or more.
- Ability to follow instructions.
- Ability to consent to study entry.
Exclusion
- Grade 3 or 4 hepatic encephalopathy.
- Untreated HIV infection.
- Previous liver transplant.
- Inability to walk.
- Extrahepatic diseases that limit mobility (e.g., neurological or musculoskeletal).
- Advanced cardiac, renal or pulmonary disease.
- Expectation of being transplanted during the study period.
- Hepatocarcinoma (HCC) exceeding the Milan criteria.
Key Trial Info
Start Date :
February 1 2023
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
December 1 2023
Estimated Enrollment :
80 Patients enrolled
Trial Details
Trial ID
NCT06149026
Start Date
February 1 2023
End Date
December 1 2023
Last Update
November 28 2023
Active Locations (1)
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1
Pontificia Universidad Catolica de Chile
Santiago, Santiago Metropolitan, Chile