Status:

ENROLLING_BY_INVITATION

18F-MFBG Cardiac Imaging for Heart Failure Administration

Lead Sponsor:

Sichuan Provincial People's Hospital

Conditions:

Rest Gated Myocardial Perfusion Imaging in Heart Failure

Eligibility:

All Genders

18-80 years

Brief Summary

The clinical feasibility of 18F-FMBG cardiac PET imaging will be observed in sympathetic nervous system activity in patients with heart failure, predicted cardiac events, guided ICD implantation, and ...

Detailed Description

This is a prospective, single-center clinical study, using18F-meta-fluorobenzylguanidine (18F-MFBG) cardiac PET imaging to present the sympathetic nerve status in heart failure, including ICD implanta...

Eligibility Criteria

Inclusion

  • 1\. Clinically confirmed patient with chronic heart failure, LVEF ≤ 40%, cardiac function NYHA 2-3 grade, survival period greater than 1 year, evaluated by the Heart Failure Center of Sichuan Provincial People's Hospital.
  • 2\. Chronic heart failure patients were evaluated by the Cardiology Department of Sichuan Provincial People's Hospital 5-10 days before ICD implantation.
  • 3\. All patients above have signed an informed consent form.

Exclusion

  • 1\. Heart failure, heart function NYHA levels ⅠOR Ⅳ.
  • 2\. The patient has already implanted ICD or CRT.
  • 3\. Heart transplant patients.
  • 4\. Patients with malignant tumors.
  • 5\. Heart valve disease.
  • 6\. Myocardial infarction occurred within the past three months.
  • 7\. The patient has contraindications for ICD implantation surgery.
  • 8\. The patient does not cooperate or is unwilling to conduct the study.

Key Trial Info

Start Date :

January 1 2024

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

December 31 2026

Estimated Enrollment :

100 Patients enrolled

Trial Details

Trial ID

NCT06149195

Start Date

January 1 2024

End Date

December 31 2026

Last Update

January 24 2024

Active Locations (1)

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Page 1 of 1 (1 locations)

1

Zhi Ling Ding

Chengdu, Sichuan, China, 610072