Status:
COMPLETED
Supervised Treadmill Intervention to Reduce Inflammation and Depression Through Exercise in HIV: The STRIDE Pilot Study
Lead Sponsor:
University of Minnesota
Conditions:
Depression
Hiv
Eligibility:
All Genders
18-45 years
Phase:
NA
Brief Summary
Depression in people living with HIV is associated with worse care engagement, drug adherence, and higher rates of pre-mature mortality. The prevalence of depression is three times greater in those wi...
Eligibility Criteria
Inclusion
- Enrolled in Mildmay HIV clinic
- Adults 18-45 years old
- HIV positive
- Receiving HIV therapy
- HIV viral suppression (\<400 copies/mL) per chart review
- Mild to Moderate (PHQ9 score \>5 but \>20)
- Not currently engaged in a formal exercise program or manual labor such as construction or delivery requiring a manual bike or walking
- Able to walk/run on a treadmill
- Informed consent
Exclusion
- Women pregnant or breastfeeding
- Suicidal (PHQ-9 question 9 score \>2) or Severely Depressed (PHQ-9 score \>20)
- Uncontrolled hypertension (≥180 systolic or ≥100 diastolic blood pressure)
- Lower limb orthopedic limitations (e.g. amputations, arthritis)
- Resting heart rate \>90/min
- Known atherosclerotic or non-atherosclerotic peripheral artery disease.
- Exercise intolerance due to other known medical condition(s) which may make it unsafe for the patients to participate in.
Key Trial Info
Start Date :
July 1 2024
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
April 15 2025
Estimated Enrollment :
22 Patients enrolled
Trial Details
Trial ID
NCT06149624
Start Date
July 1 2024
End Date
April 15 2025
Last Update
May 30 2025
Active Locations (1)
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1
University of Minnesota
Minneapolis, Minnesota, United States, 55414