Status:

UNKNOWN

Intensive Versus Standard Treatment for Spinal Anesthesia-induced Hypotension in Preeclamptic Patients

Lead Sponsor:

General Hospital of Ningxia Medical University

Conditions:

Adverse Effect

Eligibility:

FEMALE

18-45 years

Phase:

NA

Brief Summary

The objective of this study is to investigate the impact of varying maternal blood pressure maintenance targets on neonatal outcomes in preeclamptic patients following cesarean section.

Detailed Description

Post-spinal anesthesia hypotension is a frequent complication during spinal anesthesia for cesarean section. The incidence of post-spinal anesthesia hypotension is as high as 62.1-89.7% if prophylacti...

Eligibility Criteria

Inclusion

  • 18-45 years
  • Primipara or multipara
  • Singleton pregnancy ≥32 weeks
  • American Society of Anesthesiologists physical status classification I to III
  • Scheduled for cesarean section under spinal anesthesia

Exclusion

  • Baseline blood pressure ≥160 mmHg
  • Body height \< 150 cm
  • Body weight \> 100 kg or body mass index (BMI) ≥ 40 kg/m2
  • Eclampsia or chronic hypertension
  • Hemoglobin \< 7g/dl
  • Fetal distress, or known fetal developmental anomaly

Key Trial Info

Start Date :

December 5 2023

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

June 30 2024

Estimated Enrollment :

300 Patients enrolled

Trial Details

Trial ID

NCT06151431

Start Date

December 5 2023

End Date

June 30 2024

Last Update

December 15 2023

Active Locations (1)

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General Hospital of Ningxia Medical University

Yinchuan, Ningxia, China, 750004