Status:
RECRUITING
KIdney aNd blooD prESsure ouTcomes in Childhood Cancer Survivors (CCS)
Lead Sponsor:
The Hospital for Sick Children
Conditions:
Childhood Cancer
Chronic Kidney Diseases
Eligibility:
All Genders
Up to 19 years
Brief Summary
Background: Childhood cancer survivors (CCS) are at elevated risk of chronic health conditions. Chemotherapies can cause recurrent acute kidney injury which may progress to kidney fibrosis, chronic ki...
Detailed Description
Significant improvements in childhood cancer survival rates have come at the cost of an increase in chronic health conditions. Childhood cancer survivors (CCS) often experience chronic kidney disease ...
Eligibility Criteria
Inclusion
- 3 years ± 6 months after therapy for first cancer
- Received high-risk therapy for first cancer, as defined by the Canadian Oncology Group (COG) as alkylating agents; platinums; abdominal or total body radiation; high dose methotrexate; stem cell transplant; nephrectomy; or other therapy which may be known to possibly cause late kidney and/or BP effects.
Exclusion
- Pre-cancer severe CKD and/or previous kidney transplant
- \>19 years old at 3 years after cancer therapy completion
Key Trial Info
Start Date :
January 5 2024
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
December 31 2039
Estimated Enrollment :
500 Patients enrolled
Trial Details
Trial ID
NCT06153147
Start Date
January 5 2024
End Date
December 31 2039
Last Update
April 17 2024
Active Locations (1)
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1
The Hospital For Sick Children
Toronto, Ontario, Canada, M5G 1E8