Status:

RECRUITING

INtensity of OVarian Stimualtion and Euploid Embryos

Lead Sponsor:

Fundación Santiago Dexeus Font

Conditions:

Fertility

Eligibility:

FEMALE

38-42 years

Phase:

PHASE4

Brief Summary

This randomized trial was designed as a no-inferiority trial aiming to evaluate if the intensity of stimulation (a milder vs a more intense approach) may have an impact on the number of euploid embryo...

Eligibility Criteria

Inclusion

  • Infertile patients with indication for IVF
  • Undergoing preimplantation genetic screening cycles
  • AMH \>= 1.5 ng/ml and \< 3.5 ng/ml (AMH result of up to one year will be valid)
  • BMI 18.5 - 30 Kg/m2

Exclusion

  • Severe male factor requiring TESE (testicular sperm extraction)
  • AMH \< 1.5 ng/ml or \>= 3.5 ng/ml
  • Administration of any other drug potentially interfering with the treatment
  • Contraindication for hormonal treatment
  • Recent history of severe disease requiring regular treatment (clinically significant concurrent medical condition that could compromise subject safety or interfered with the trial assessment).
  • Monogenic disease to be detected with PGT-M

Key Trial Info

Start Date :

December 12 2023

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

May 15 2026

Estimated Enrollment :

110 Patients enrolled

Trial Details

Trial ID

NCT06154083

Start Date

December 12 2023

End Date

May 15 2026

Last Update

February 27 2025

Active Locations (1)

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1

Hospital Universitario Quiron Dexeus

Barcelona, Spain, 08028