Status:

UNKNOWN

Exploring the Use of Pulse Tissue Doppler in Predicting Extubation Success in Mechanically Ventilated Patients

Lead Sponsor:

Affiliated Hospital of Jiangnan University

Conditions:

Airway Extubation

Eligibility:

All Genders

18+ years

Brief Summary

Determining the appropriate extubation timing for mechanically ventilated patients is a critical issue in the Intensive Care Unit (ICU). Early or delayed extubation may prolong mechanical ventilation ...

Detailed Description

All patients included in the study underwent a spontaneous breathing trial (SBT) using pressure support ventilation (PSV) strategy. This strategy employed pressure support(PS)≤9 cmH2O and positive end...

Eligibility Criteria

Inclusion

  • Patients were enrolled if participants had been intubated and mechanically ventilated for more than 24 hours and were ready for participants first SBT according to ICU weaning criteria.

Exclusion

  • paralytic drugs taken within 24 hours prior to the trial;
  • diagnosis of diaphragmatic paralysis or paradoxical movement of the hemidiaphragm detected by ultrasound or poor imaging quality;
  • Pregnancy;
  • Ascites;
  • age\<18years;
  • Post-thoracotomy;
  • Existence of pneumothorax;
  • presence of large pleural effusion, subcutaneous emphysema, flail chest or right-sided rib fractures;
  • presence of neuromuscular diseases.

Key Trial Info

Start Date :

September 1 2022

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

December 1 2024

Estimated Enrollment :

200 Patients enrolled

Trial Details

Trial ID

NCT06154811

Start Date

September 1 2022

End Date

December 1 2024

Last Update

December 8 2023

Active Locations (1)

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1

Affiliated Hospital of Jiangnan University

Wuxi, Jiangsu, China, 214122