Status:
COMPLETED
Efficacy of Accelerated Repetitive Transcranial Magnetic Stimulation on Patients With Post-stroke Depression
Lead Sponsor:
Ankara City Hospital Bilkent
Conditions:
Post-stroke Depression
Eligibility:
All Genders
18-75 years
Phase:
NA
Brief Summary
The FDA approved repetitive transcranial magnetic stimulation (rTMS) for patients with Major Depressive Disorder (MDD) in 2008. The conventional rTMS protocol that has been used effectively for major ...
Detailed Description
Objective: Depression is a complication that negatively affects the quality of life and functional recovery of stroke patients and is associated with increased physical disability, cognitive and socia...
Eligibility Criteria
Inclusion
- Ischemic stroke in only one hemisphere is diagnosed by MRI,
- Ischemic stroke within 1-6 months,
- Diagnosis of major depression according to DSM-5 diagnostic criteria by a psychiatrist during post-stroke evaluations,
- Hamilton Depression Rating Scale (HAMD) score of ≥8 as assessed by a clinical psychologist, despite receiving at least one antidepressant treatment,
- Drug use should be stable for at least 2 weeks before accelerated rTMS treatment for depression treatment and no change in drug dose should be made for 6 weeks following treatment,
- Mini mental test score ≥ 24
Exclusion
- Known history of epilepsy, dementia, cognitive impairment, neurodegenerative disease,
- İntracranial metallic implant (cochlear implant, brain pacemaker, drug pump, etc.),
- Lesions in the brain due to vascular, traumatic, tumoral or infectious reasons,
- Recurrent strokes,
- Aphasia,
- Alcoholism,
- Pregnancy,
- Cardiac pacemaker,
- Patients diagnosed with psychiatric diseases other than depression
Key Trial Info
Start Date :
February 7 2022
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
July 11 2023
Estimated Enrollment :
24 Patients enrolled
Trial Details
Trial ID
NCT06157333
Start Date
February 7 2022
End Date
July 11 2023
Last Update
December 5 2023
Active Locations (1)
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1
Ankara Bilkent City Hospital
Ankara, Turkey (Türkiye), 06800