Status:
COMPLETED
ED90 of Norepinephrine and Phenylephrine Infusions Under Intensive Treatment
Lead Sponsor:
General Hospital of Ningxia Medical University
Conditions:
Adverse Effect
Eligibility:
FEMALE
18-45 years
Phase:
NA
Brief Summary
The objective of this study is to investigate the ED90 of norepinephrine and phenylephrine infusions for preventing postspinal anesthesia hypotension under intensive treatment during cesarean section
Detailed Description
Post-spinal anesthesia hypotension is a frequent complication during spinal anesthesia for cesarean section. The incidence of post-spinal anesthesia hypotension is as high as 62.1-89.7% if prophylacti...
Eligibility Criteria
Inclusion
- 18-45 years
- Primipara or multipara
- Singleton pregnancy ≥37 weeks
- American Society of Anesthesiologists physical status classification I to II
- Scheduled for cesarean section under spinal anesthesia
Exclusion
- Body height \< 150 cm
- Body weight \> 100 kg or body mass index (BMI) ≥ 40 kg/m2
- Eclampsia or chronic hypertension or baseline blood pressure ≥180 mmHg
- Hemoglobin \< 7g/dl
- Fetal distress, or known fetal developmental anomaly
Key Trial Info
Start Date :
January 1 2025
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
April 30 2025
Estimated Enrollment :
60 Patients enrolled
Trial Details
Trial ID
NCT06158048
Start Date
January 1 2025
End Date
April 30 2025
Last Update
May 25 2025
Active Locations (1)
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1
General Hospital of Ningxia Medical University
Yinchuan, Ningxia, China, 750004