Status:

RECRUITING

Sex Differences in the Vascular Effects of E-cigarette Use

Lead Sponsor:

Anna Stanhewicz, PhD

Conditions:

E-cigarette Use

Eligibility:

All Genders

18-24 years

Phase:

EARLY_PHASE1

Brief Summary

The use of electronic nicotine delivery systems, or e-cigarettes - colloquially referred to as "vaping" - in the United States has increased exponentially since their introduction to the US market in ...

Eligibility Criteria

Inclusion

  • 18-24 years old
  • one of the following:
  • have no history of e-cigarette use
  • be a current e-cigarette user who has been using e-cigarettes for 6 months or longer

Exclusion

  • history of cardiovascular, metabolic, and/or skin diseases
  • body mass index \>30 kg/m2
  • blood pressure ≥140 systolic and/or ≥ 90 diastolic
  • current or history of tobacco cigarette use
  • current antihypertensive or cholesterol-lowering medication
  • current use of cannabis, marijuana, and/or other illegal substances
  • current use of stimulant drugs
  • currently pregnant or breastfeeding
  • allergy to materials used during the experiment (e.g. latex),
  • known allergy to study drugs
  • healthy control subjects will also be excluded if they have ever used e-cigarettes in the past

Key Trial Info

Start Date :

December 2 2023

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

December 1 2026

Estimated Enrollment :

80 Patients enrolled

Trial Details

Trial ID

NCT06159608

Start Date

December 2 2023

End Date

December 1 2026

Last Update

December 15 2025

Active Locations (1)

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Page 1 of 1 (1 locations)

1

University of Iowa

Iowa City, Iowa, United States, 52242