Status:
UNKNOWN
Characteristics of Hypophosphatasia in Adult Patients in Rheumatology
Lead Sponsor:
University of Bonn
Conditions:
Hypophosphatasia
Eligibility:
All Genders
18+ years
Brief Summary
With hypophosphatasia still being frequently overlooked and misdiagnosed, the primary aim of this prospective observational study is to determine the prevalence of hypophosphatasia in adult patients i...
Detailed Description
Hypophosphatasia (HPP) is a rare genetic disorder (1-3/300,000 severe cases in Europe) caused by one or more mutations in the alkaline phosphatase (ALP) gene. Hypomineralization results in symptoms su...
Eligibility Criteria
Inclusion
- Written Informed consent
- Age \> 18 years
- Clinical suspicion of hypophosphatasia
- Evidence of a pathological ALP value within the clinical routine screening
Exclusion
- Failure to meet the inclusion criteria listed above
Key Trial Info
Start Date :
February 28 2023
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
December 1 2024
Estimated Enrollment :
60 Patients enrolled
Trial Details
Trial ID
NCT06161142
Start Date
February 28 2023
End Date
December 1 2024
Last Update
December 7 2023
Active Locations (1)
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1
Clinic of Internal Medicine III, Department of Oncology, Haematology, Rheumatology and Clinical Immunology, University Hospital Bonn
Bonn, North Rhine-Westphalia, Germany, 53127