Status:
RECRUITING
Periodontal Regeneration With Recombinant Human Platelet Derived Growth Factor (rH-PDGF-BB) and Allograft
Lead Sponsor:
Universidad Autonoma de Nuevo Leon
Collaborating Sponsors:
LifeNet Health
Lynch Biologics LLC
Conditions:
Periodontal Diseases
Eligibility:
All Genders
18+ years
Phase:
PHASE2
Brief Summary
Growth factors are defined as small proteins that trigger a cellular response after binding to cell receptors; Tissue engineering is now clinically applicable in a commercially available system involv...
Detailed Description
The study will be performed in 30 periodontal defects of 2 and 3 walls. The experimental group will consist of DFDBA placement with rhPDGF-BB and control DFDBA with saline solution. The clinical param...
Eligibility Criteria
Inclusion
- Clinical diagnosis of periodontitis
- Infrabony defects of 2 walls, 3 walls and combined defects
- Patients ASA (American Society of Anesthesiologists) I and II
- Patients who smoke less than 10 cigarettes
Exclusion
- Patients undergoing bisphosphonate therapy
- Furcation defects
- Patients with evidence of blood dyscrasias.
- Pregnant patient
Key Trial Info
Start Date :
January 10 2024
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
January 15 2025
Estimated Enrollment :
30 Patients enrolled
Trial Details
Trial ID
NCT06162832
Start Date
January 10 2024
End Date
January 15 2025
Last Update
May 1 2024
Active Locations (1)
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1
Posgrado de Periodoncia, Facultad de Odontología, Universidad Autónoma de Nuevo León
Monterrey, Nuevo León, Mexico, 64460