Status:

TERMINATED

Blue and Amber Light Exposure in Patients With Rectal and Pancreatic Cancer

Lead Sponsor:

Matthew Neal MD

Conditions:

Pancreatic Neoplasms

Rectal Neoplasms

Eligibility:

All Genders

19-80 years

Phase:

NA

Brief Summary

This study will evaluate light therapy used in combination with standard therapies for pancreatic and rectal cancer. Participants will receive chemotherapy, radiation, and surgical treatments identica...

Detailed Description

The investigators incorporate appropriate control participants, which include participants who are matched for stage and age and who undergo neoadjuvant chemoradiation and/or surgery but who are not e...

Eligibility Criteria

Inclusion

  • greater than 18 and less than 80 years of age
  • adenocarcinoma of the pancreas (unresectable) or adenocarcinoma of the rectum (stage II or III).

Exclusion

  • Prior chemotherapy (inability to determine the integrity of the immune response)
  • Autoimmune disorder, immunosuppression therapy, or immunocompromised state (inability to determine the integrity of the immune response)
  • Blindness or other significant vision disorder or prior traumatic brain injury (the inability to determine the integrity of functional optic and suprachiasmatic pathways)
  • Hematological disease - e.g., myelodysplastic syndrome, leukemia (inability to determine the integrity of the immune response)
  • Bipolar disorder or schizophrenia (potential heightened symptoms)
  • Refusal/ineligible to undergo neoadjuvant chemotherapy and/or radiation

Key Trial Info

Start Date :

August 14 2022

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

April 29 2023

Estimated Enrollment :

2 Patients enrolled

Trial Details

Trial ID

NCT06164691

Start Date

August 14 2022

End Date

April 29 2023

Last Update

May 21 2024

Active Locations (1)

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Page 1 of 1 (1 locations)

1

University of Pittsburgh Medical Center

Pittsburgh, Pennsylvania, United States, 15213