Status:

RECRUITING

GRACE: Evaluating Compression Stockings in Patients That Require Extended Duration Pharmacological Thromboprophylaxis

Lead Sponsor:

Imperial College London

Collaborating Sponsors:

National Institute for Health Research, United Kingdom

Conditions:

Venous Thromboembolism

Surgery

Eligibility:

All Genders

18+ years

Phase:

NA

Brief Summary

Individuals attending the hospital to undergo operations are at risk of developing blood clots in the legs, known as deep vein thrombosis (DVT). A clot in the leg can cause swelling, pain, and other l...

Detailed Description

Research question: Is it beneficial to provide graduated compression stockings (GCS) in addition to extended duration pharmacological thromboprophylaxis (EDPTP) for surgical patients at highest risk o...

Eligibility Criteria

Inclusion

  • Adults (≥18 years of age)
  • Participants undergoing elective surgery; risk assessed as requiring EDPTP

Exclusion

  • Contraindications to EDPTP or GCS
  • Individuals requiring therapeutic anticoagulation e.g., anticoagulation for previous DVT
  • Known thrombophilia or thrombogenic disorder

Key Trial Info

Start Date :

April 27 2024

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

March 31 2027

Estimated Enrollment :

8608 Patients enrolled

Trial Details

Trial ID

NCT06166537

Start Date

April 27 2024

End Date

March 31 2027

Last Update

May 16 2024

Active Locations (3)

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Page 1 of 1 (3 locations)

1

North Bristol NHS Trust

Bristol, United Kingdom

2

Imperial College Healthcare NHS Trust

London, United Kingdom

3

University College London NHS Trust

London, United Kingdom

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