Status:
RECRUITING
Capture of Healthy Gut Bacteria Associated to High Fiber Diet
Lead Sponsor:
Institut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement
Collaborating Sponsors:
Centre de Recherche en Nutrition Humaine d'Auvergne
Conditions:
General Population
Eligibility:
All Genders
20-50 years
Brief Summary
The role of the intestinal microbiota on health is now well recognised, and diet is one of the factors influencing the maintenance of a healthy intestinal microbiota. More specifically, the consumptio...
Detailed Description
Since two decades, numerous studies have been performed to better understand the role of the gut microbiota in health and disease. An imbalance in the intestinal microbiota, known as dysbiosis, is fre...
Eligibility Criteria
Inclusion
- Healthy adult subjects ;
- Age between 20 and 50 (limits included) ;
- BMI between 18.5 and 25 kg/m2 (excluding limits) ;
- Consumption of more than 5 portions of fruit and vegetables a day;
- Intake of at least 25g of dietary fibre per day;
- A varied diet with little processed food.
Exclusion
- Antibiotics and/or transit modulators taken in the 3 months prior to sampling;
- Known pathologies;
- Current treatment;
- History of digestive surgery having an impact on the microbiota, deemed incompatible with the study (bariatric surgery);
- Consumption of food supplements based on protein preparations, probiotics or prebiotics;
- Smoking (even occasionally);
- Alcohol consumption \> 2 glasses (i.e. 20 g) per day;
- Intense sporting activity;
- Pregnant or breast-feeding women;
- Persons under legal protection (curatorship, guardianship, etc.);
- Volunteers taking part in another intervention study;
- Persons refusing to be registered on the French Ministry of Health's Fichier National des Volontaires Sains (National Register of Healthy Volunteers);
- Subject not affiliated to the social security system;
- Subject in a period of exclusion from a previous study or having received a total amount of compensation exceeding 6000 euros over the 12 consecutive months prior to the start of the trial (after verification in the Fichier des Volontaires pour la Recherche Biomédicale).
Key Trial Info
Start Date :
October 24 2023
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
January 31 2026
Estimated Enrollment :
10 Patients enrolled
Trial Details
Trial ID
NCT06166810
Start Date
October 24 2023
End Date
January 31 2026
Last Update
December 22 2025
Active Locations (1)
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1
CRNH Auvergne
Clermont-Ferrand, France, 63009