Status:

RECRUITING

A Safety and Effectiveness Prospective Blinded Clinical Study to Validate xBar System as Monitoring Tool for Anastomotic Leaks Detection

Lead Sponsor:

Exero Medical Ltd.

Conditions:

Colorectal Surgery

Anastomotic Leak

Eligibility:

All Genders

22+ years

Phase:

NA

Brief Summary

Purpose: To validate the safety and effectiveness of xBar monitoring tool for detection of post-operative anastomotic leaks in subjects undergoing rectal/sigmoid resections with anastomosis. The clin...

Detailed Description

Study design: Pivotal, Prospective, Blinded, multi-center study. Study Population: This study will enroll approximately 190 eligible subjects undergoing scheduled colorectal surgery with anastomosis, ...

Eligibility Criteria

Inclusion

  • Age ≥ 22 years
  • Indication for sigmoid or rectal resection surgery.
  • Usage of drain during the surgery (to be confirmed during the surgery)
  • Willing and able to comply with the study follow up.
  • Able and agree to provide an informed consent.

Exclusion

  • Contraindication for surgery and/or general anesthesia.
  • Pregnancy or lactation.
  • Planned or unplanned fecal diversion during the surgery (to be confirmed during the surgery)
  • Known electronic device implanted in the chest or the abdominal cavity (e.g., pacemaker, cardioverter/defibrillator).
  • Major medical or psychiatric illness or condition, or other factors that may affect general health or ability to adhere to the follow-up schedule.
  • Known allergic reactions to materials used in the components of the xBar system, i.e., silicone, rubber and stainless-steel.
  • Participation in another interventional study during the xBar system usage.

Key Trial Info

Start Date :

March 11 2023

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

December 1 2025

Estimated Enrollment :

190 Patients enrolled

Trial Details

Trial ID

NCT06168669

Start Date

March 11 2023

End Date

December 1 2025

Last Update

September 30 2025

Active Locations (13)

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Page 1 of 4 (13 locations)

1

AdventHealth Orlando

Orlando, Florida, United States, 328803

2

AdventHealth Tampa

Tampa, Florida, United States, 33613

3

University of Louisville

Louisville, Kentucky, United States, 40202

4

Henry Ford Health

Detroit, Michigan, United States, 48202

A Safety and Effectiveness Prospective Blinded Clinical Study to Validate xBar System as Monitoring Tool for Anastomotic Leaks Detection | DecenTrialz