Status:

RECRUITING

Effect of Nitrate Supplementation on Blood Pressure and Microvascular Function of Resistant Hypertensive Patients

Lead Sponsor:

National Institute of Cardiology, Laranjeiras, Brazil

Conditions:

Arterial Hypertension

Resistant Hypertension

Eligibility:

All Genders

18-75 years

Phase:

EARLY_PHASE1

Brief Summary

Arterial hypertension (AH) has been identified as an important public health problem and considered a new epidemic with high mortality and morbidity. High blood pressure (BP) levels increase the chanc...

Eligibility Criteria

Inclusion

  • Resistant hypertension, with a diagnosis described in the medical record, without changing medications or increasing doses in the last 30 days.

Exclusion

  • neoplasms
  • heart failure
  • use of medications with nitrate in their formula
  • patients undergoing renal denervation

Key Trial Info

Start Date :

November 1 2023

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

December 1 2025

Estimated Enrollment :

50 Patients enrolled

Trial Details

Trial ID

NCT06169241

Start Date

November 1 2023

End Date

December 1 2025

Last Update

May 22 2025

Active Locations (1)

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Page 1 of 1 (1 locations)

1

National Institute of Cardiology

Rio de Janeiro, Brazil, 21040-360