Status:
RECRUITING
Incidence of Acute Kidney Injury After Administration of Iodine Contrast Media in Patients With Reduced Renal Function
Lead Sponsor:
Uppsala University
Conditions:
Acute Kidney Injury Following Administration of Contrast Media
Eligibility:
All Genders
18+ years
Brief Summary
This study is examining if injection of iodine contrast media increases the risk of acute kidney injury in patients with severely reduced renal function. All patients who have a medical need for a com...
Detailed Description
This is a single centre prospective cohort study performed at a tertiary level, university hospital in Sweden. Background data included age, sex, height, and weight. Body surface area (BSA) is calcul...
Eligibility Criteria
Inclusion
- eGFR \<30 mL/min/1.73m2, calculated with the revised Lund-Malmö formula and plasma creatinine.
- Medical need of either an ICM-enhanced or unenhanced CT
Exclusion
- \<18 years of age
- Ongoing renal replacement therapy
- Ongoing treatment with nephrotoxic drugs. Drugs classified as nephrotoxic are acyclovir, aminoglycosides, ciclosporins, cisplatin, methotrexate, non-steroidal anti-inflammatory drugs (except low-dose aspirin) and vancomycin administered intravenously.
- Known allergy to ICM who and have not received prophylactic treatment (if patient belongs to ICM arm)
Key Trial Info
Start Date :
January 24 2024
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
December 31 2025
Estimated Enrollment :
400 Patients enrolled
Trial Details
Trial ID
NCT06171958
Start Date
January 24 2024
End Date
December 31 2025
Last Update
May 20 2024
Active Locations (1)
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1
Uppsala University
Uppsala, Sweden, 751 85