Status:

COMPLETED

A Study to Evaluate the Consistency of Oscillometry and Spirometry Test Results in Patients With Confirmed or Suspected Asthma or COPD

Lead Sponsor:

AstraZeneca

Conditions:

Asthma/ COPD

Eligibility:

All Genders

18+ years

Brief Summary

The study to evaluate the consistency of oscillometry and spirometry test results in patients with confirmed or suspected asthma or COPD, it is a multi-centre clinical study. sponsor by Astrazeneca In...

Detailed Description

800 patients, including suspected or confirmed asthma, suspected or confirmed COPD, will be enrolled in nationwide multiple study centres. Enrolling suspected and confirmed subject in an approximate1:...

Eligibility Criteria

Inclusion

  • Participants are eligible to be included in the study only if all of the following criteria apply and signed informed content :
  • Suspected and confirmed asthma
  • Participant must be≥18 years old.
  • Present symptom such as wheezing, cough, chest tightness, shortness of breath, but not confirmed-asthma (without evidence of variable airflow restriction) or confirmed-asthma with evidence of variable airflow restriction (such as positive bronchodilation test, positive bronchial challenge test, variability \>10% in twice daily PEF over 2 weeks, et al) Suspected and confirmed COPD
  • 1 Participant must be ≥40 years old. 2 Present symptom such as chronic cough, sputum production, dyspnoea, but not confirmed-COPD (without evidence of persistent airflow restriction) or confirmed- COPD with evidence of persistent airflow restriction (post-bronchodilator FEV1/FVC\<0.7)

Exclusion

  • Participants are excluded from the study if any of the following criteria apply:
  • Any diseases that influence lung function result such as lung cancer, pneumonia, active pulmonary tuberculosis, pulmonary embolism and interstitial lung disease, etc; history of recent surgery that affect lung function results, including thoracotomy surgery, pneumothorax surgery, thoracic drainage, etc
  • Contraindication to spirometry or oscillometry test, or allergic to bronchodilator.
  • Currently pregnant or breast-feeding women
  • Judge by the investigator if the participant is unlikely to comply with study procedures, restrictions, and requirements, will not be enrolled .

Key Trial Info

Start Date :

February 8 2024

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

August 30 2024

Estimated Enrollment :

801 Patients enrolled

Trial Details

Trial ID

NCT06172777

Start Date

February 8 2024

End Date

August 30 2024

Last Update

July 24 2025

Active Locations (41)

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Page 1 of 11 (41 locations)

1

Research Site

Beijing, China

2

Research Site

Changsha, China

3

Research Site

Chengdu, China

4

Research Site

Chongqing, China

A Study to Evaluate the Consistency of Oscillometry and Spirometry Test Results in Patients With Confirmed or Suspected Asthma or COPD | DecenTrialz