Status:
UNKNOWN
The Effect of Gastric Emptying on Blood Glucose Profile of Type 1 Diabetes Mellitus and Its Therapeutic Strategies
Lead Sponsor:
Nanjing First Hospital, Nanjing Medical University
Conditions:
Diabetes
Eligibility:
All Genders
Up to 70 years
Phase:
NA
Brief Summary
Establish a cohort study to describe the characteristics of gastric emptying in patients with type 1 diabetes, and adjust the timing of insulin injection during meals to improve blood glucose fluctuat...
Detailed Description
1\. T1DM that met the inclusion criteria was tested with baseline blood routine, biochemical and complication screening, and FGM monitoring for 14 days (patient blindness) on the basis of the original...
Eligibility Criteria
Inclusion
- Volunteer and sign subject informed consent prior to the trial.
- Patients with type 1 diabetes, aged less than 70 years, 7%≤HbA1c≤9.0%.
- There were no acute complications such as diabetic ketoacidosis and diabetic hypertonic syndrome.
- Subjects were able and willing to undergo 14-day scanning blood glucose monitoring, diet and exercise routine.
Exclusion
- Patients with severe gastrointestinal symptoms, history of gastrointestinal disease, surgical history, or impaired liver and kidney function.
- Patients who have used drugs that affect gastrointestinal function or appetite in the last week.
- History of drug abuse and alcohol dependence within the past 5 years.
- Systemic hormone therapy was used in the last three months.
- Patients with poor compliance, irregular diet and exercise.
- Patients with infection and stress within four weeks.
- Patients who could not tolerate 14-day scanning blood glucose monitoring.
- Patients who are pregnant, nursing or intending to become pregnant.
- Any other obvious condition or comorbidities determined by the investigator: such as serious cardiopulmonary disease, endocrine disease, neurological, neoplastic, other pancreatic disease, history of mental illness.
Key Trial Info
Start Date :
December 1 2023
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
December 31 2025
Estimated Enrollment :
50 Patients enrolled
Trial Details
Trial ID
NCT06173934
Start Date
December 1 2023
End Date
December 31 2025
Last Update
December 18 2023
Active Locations (1)
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1
Nanjing First Hospital, Nanjing Medical University
Nanjing, Jiangsu, China