Status:
UNKNOWN
An Exploratory Study of Visual Function Rehabilitation in Patients With Ocular Trauma
Lead Sponsor:
Zhongshan Ophthalmic Center, Sun Yat-sen University
Conditions:
Eye Injuries
Eligibility:
All Genders
3-60 years
Phase:
NA
Brief Summary
Ocular trauma is one of the leading causes of blindness worldwide, often resulting in severe visual impairment or even loss of vision after injury. Although after powerful surgical treatment, there a...
Detailed Description
Perceptual training is a type of perceptual learning that initiates neural modifications during continuous repetitive task training, thereby increasing neural efficiency and improving the visual proce...
Eligibility Criteria
Inclusion
- Retinopathy, optic neuropathy, endophthalmitis and other injuries caused by ocular trauma, with varying degrees of central vision reduction and visual field impairment
- Age 3\~60 years old
- Best corrected visual acuity of the affected eye: 20/200≤BCVA≤20/25
- Intraocular pressure is normal, non-hypotonal/atrophic: 7--21mmHg
- After the traumatic injury, the condition is stable ≥for 3 months after treatment, and the visual axis has a complete and transparent optical pathway
- If the patient is injured in one eye, There were no abnormal lesions in the contralateral eye, no abnormalities in slit lamp and indirect ophthalmoscopy, and no peripheral retinopathy in both eyes was found on triprimmoscopy. Carefully ask for a history of no other eye disease in both eyes and a systemic history that has caused an associated eye disease or has affected visual formation.
- The cranial structure is intact, the function is good, and there is no primary or secondary injury
- Able to cooperate with the questionnaire and treatment, good compliance
- Those who are willing to sign the informed consent form
Exclusion
- Have active inflammation of the eye
- Previous abnormal intraocular blood supply such as occlusion of the central intraocular artery due to trauma or non-traumatic factors
- History of other non-traumatic intraocular surgery
- Ocular related lesions caused by other non-traumatic factors that can interfere with this study, such as age-related macular degeneration, glaucoma, amblyopia, etc.
- Use of other rehabilitation training methods or visual aids 3 months before enrollment
- Lesions with systemic diseases whose degree of lesions have affected visual function, such as diabetic retinopathy, Hypertension and arteriosclerotic fundus changes, rubella-related ocular changes, etc.
- Patients with severe systemic diseases such as renal failure and malignant hypertension or may affect visual function (such as retinal structure and function, choroidal structure and function, etc.)
- Patients with congenital ocular lesions
- Patients with optic nerve and retinopathy caused by non-traumatic factors
- Patients with cranial brain disease or craniocere-related lesions with poor cortical function
- Psychological related diseases
- MRI contraindications, Such as claustrophobia and non-MRI compatible metal implants
- people with speech impairment and intellectual disability
- those who are considered inappropriate by the investigator
Key Trial Info
Start Date :
December 30 2023
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
April 30 2024
Estimated Enrollment :
20 Patients enrolled
Trial Details
Trial ID
NCT06174415
Start Date
December 30 2023
End Date
April 30 2024
Last Update
December 18 2023
Active Locations (1)
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1
Zhonshan Ophthalmic Center, Sun Yat-Sen University
Guangzhou, Guangdong, China