Status:
UNKNOWN
Diaphragm Dysfunction After COVID-19 as Determined by Dynamic Chest Radiography
Lead Sponsor:
Nanfang Hospital, Southern Medical University
Conditions:
Long Covid19
Eligibility:
All Genders
18+ years
Brief Summary
Dynamic chest radiography (DCR) is a rapid and easily performed technique that captures real-time continuous images of the moving chest. COVID-19 has led to various complications and long-term effects...
Detailed Description
It has been estimated that approximately 80% of individuals infected with the new coronavirus will experience one or more long-term symptoms following recovery, with dyspnea being a frequent clinical ...
Eligibility Criteria
Inclusion
- COVID-19 group:
- Voluntarily sign the informed consent form;
- Aged equal to or older than 18 years old, regardless of gender;
- Inpatients with COVID-19 who mainly complain of dyspnea, dyspnea If it persists or develops and lasts for more than 4 weeks after acute COVID-19, it is related to long COVID-19; (confirmed infection with COVID-19 through nucleic acid monitoring or hospital laboratory data);
- Lung function measurements have been completed during hospitalization due to diagnosis and treatment needs;
- Be able to cooperate in completing the dynamic chest X-ray (complete the positioning of the dynamic chest X-ray for 20 seconds, and breathe calmly and forcefully during this period; be able to hold breath for at least 7 seconds).
- Control group:
- Voluntarily sign the informed consent form;
- Aged equal to or older than 18 years old, regardless of gender;
- People from the health examination center, and the age, gender are matched in the COVID-19 group and have no previous acute or chronic cardiopulmonary disease, no abnormalities in previous lung physical examinations and lung imaging examinations, and no history of infectious diseases in the past month;
- Physical examination items are required People who are suitable for ordinary chest X-ray examination;
- Be able to cooperate in completing dynamic chest X-ray (complete dynamic chest X-ray positioning for 20 seconds, during which period, breathe calmly and forcefully, and be able to hold breath for at least 7 seconds).
Exclusion
- COVID-19 group:
- Not suitable to participate in this study;
- Combined with serious life-threatening diseases, such as cardiovascular and cerebrovascular diseases, lung cancer, airway obstruction, etc.;
- Combined with pneumothorax, pulmonary insufficiency, chronic disease, interstitial disease, lung surgery history or recent planned surgery;
- Mental disorder and unable to cooperate with the operator;
- Pregnant or lactating women;
- Major radiation related to the research within 12 months before consent Exposure (participating in previous studies involving radiation exposure, the research dose is limited to 0.4mSv);
- No evidence of having been infected with the new coronavirus;
- Unable to cooperate in completing dynamic chest X-rays;
- Unable to complete lung function measurements；
- Control group:
- Not suitable to participate in this study;
- Patients with previous acute or chronic cardiopulmonary disease, previous lung physical examination, lung imaging examination abnormalities, within the past 1 month Have a history of infectious diseases;
- Mentally abnormal and unable to cooperate with the operator;
- Pregnant or lactating women;
- Significant radiation exposure related to the research within 12 months before consent (participation in previous research involving radiation exposure, The study dose is limited to 0.4mSv); 6) Unable to cooperate in completing dynamic chest X-ray;.
Key Trial Info
Start Date :
November 10 2023
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
March 10 2025
Estimated Enrollment :
24 Patients enrolled
Trial Details
Trial ID
NCT06175455
Start Date
November 10 2023
End Date
March 10 2025
Last Update
December 26 2023
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
Yudong
Guangzhou, Guangdong, China